Immodgel Archives - PROTiP Medical

Press Release: Antimicrobial Film for Future Implants

A novel antimicrobial/anti-inflammatory coating developed by Protip in collaboration with University of Strasbourg, INSERM and University of Heidelberg has been covered widely by national and international press. Polyarginine/ Hyaluronic acid based polyelectrolyte multilayers have not only an antibacterial activity but also they attenuate the pro-inflammatory cytokine release by human macrophages.

Antimicrobial pres release head

For more information, please visit: INSERM Press Release Link

A short video explaining the development of the coating can be found here: Video Link (in French with English subtitles)

The related scientific publication in Advanced Healthcare Materials can be found here: Link to the article

Publications

List of publications in 2014

N.E. Vrana A. Dupret-Bories, P. Schultz, C. Debry, D. Vautier, P. Lavalle. Titanium Microbead-based Porous Implants: Bead Size Controls Cell Response and Host integration. Advanced Healthcare Materials 2014: 3(1): 79-87. Link to the article
N.E. Vrana, O. Erdemli, G. Francius, A. Fahs, M. Rabineau, C. Debry, A. Tezcaner, D. Keskin, P. Lavalle, Double Entrapment of Growth Factors by Nanoparticles Loaded into Polyelectrolyte Multilayer Films Journal of Materials Chemistry Part B 2014: 2(8): 999-1008. Link to the article
1. N. Sananes, R. Ruano, AS Weingertner, P. Regnard, Y. Salmon, A. Kohler, C. Miry, C. Mager, F. Guerra, A. Schneider, F. Becmeur, J. Leroy, JL Dimarcq, C. Debry, R. Favre, Experimental fetal encoscopic tracheal occlusion in rhesus and cynomolgus monkey’s : nonhuman primate models. J. Matern Fetal Neonatal Med. 2014 Oct 10: 1-6. Link to the article
A. Hasan, A. Paul, N.E. Vrana, X. Zhao, A. Memic, Y.S. Hwang, M.R. Dokmeci, A. Khademhosseini. Microfluidic Techniques for Development of 3D Vascularized Tissue, Biomaterials 2014: 35(26): 7308-7325. Link to the article
J. Barthes, H. Ozcelik, M. Hindie, A. Ndreu-Halili, A. Hasan, N.E. Vrana. Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine: The Recent Advances, BioMed Research International 2014: Vol. 2014: 921905. Link to the article
N.E. Vrana,V. Hasirci, G.B. McGuinness, A. Ndreu-Halili. Editorial: Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models, BioMed Research International 2014: Volume 2014: 951626. Link to the article
C. Debry, A. Dupret-Bories, N.E. Vrana, P. Hemar, P. Lavalle, P. Schultz. Larnygeal Replacement with an Artificial Larynx after Total Laryngectomy: The Possibility of Restoring Larynx Functionality in the Future, Head & Neck 2014:36(11):1669-1673. Link to the article
L.E. Bertassoni, J.C. Cardoso, V. Manoharan, A.L. Cristino, N.S. Bhise, W.A. Araujo, P. Zorlutuna, N.E. Vrana, A.M. Ghaemmaghami, M.R. Dokmeci, A. Khademhosseini. Direct-write Bioprinting of Cell-laden Methacrylated Gelatin Hydrogels, Biofabrication 2014: 6(2), 024105. Link to the article

For Full-text requests, please contact Dr. Nihal Engin Vrana at e.vrana@protipmedical.com

Publications

List of publications in 2015

E. Rieger, A. Dupret-Bories, L. Salou, M.H. Metz-Boutigue, P. Layrolle, C. Debry, P. Lavalle, N.E. Vrana. Controlled implant/soft tissue interaction by nanoscale surface modifications of 3D porous titanium implants Nanoscale 2015:7: 9908-9918. Link to the article
S. Dietemann, C. Debry, A. Onea, I.J. Namer, A. Imperiale. Epiglottic Squamous Cell Carcinoma Showing Unexpected 18F-FDOPA Uptake on PET/CT. Clin. Nucl. Med. 2015: 40 (7): e370-1. Link to the article
H. Ozcelik, N.E. Vrana, A. Gudima, V. Ryabov, A. Gratchev, Y. Haikel, M.H. Metz-Boutigue, A. Carradò, J. Faerber, T. Roland, H. Klüter, J. Khyzshkowska, P. Schaaf, P. Lavalle. Harnessing the Multifunctionality in Nature: An Antimicrobial Agent Release System with Self-antimicrobial and Anti-inflammatory Properties, Advanced Healthcare Materials 2015:13: 2026-2036 Link to the article
J. Barthes, N.E. Vrana, H. Ozcelik, J. Bacharouche, G. Francius, J. Hemmerlé, B. Senger, M.H. Metz-Boutigue, P. Schaaf, P. Lavalle. Priming the Cells for Their Final Destination: Microenvironment Controlled Cell Culture by a Modular ECM-mimicking Feeder Layer, Biomaterials Science 2015:3: 1302-1311. Link to the article
H.M. Rostam, S. Singh, N.E. Vrana, M. Alexander, A. Ghaemmaghami. Impact of Surface Chemistry and Topography on the Function of Antigen Presenting Cells, Biomaterials Science 2015:3: 424-441. Link to the article
J. Kzhyshkowska, S. Gudima, V. Riabov, C. Dollinger, P. Lavalle, N.E. Vrana. Macrophage responses to implants: Perspectives for personalized medicine, Journal of Leukocyte Biology 2015: 98:953-962. Link to the article

For Full-text requests, please contact Dr. Nihal Engin Vrana at e.vrana@protipmedical.com

Events

Conference Presentation: e-MRS 2016 Lille France

We will participate in European Material Research Society (e-MRS) 2016 meeting which will in Lille, France with an oral presentation (2-6 May 2016).

Our recent work on implant epithelialization entitled “Re-epithelialization of Respiratory System Implants: Gelatin-based Epithelial Patches with a Connective Tissue Component” will be presented by Dr. Sait Ciftci (Hôpital de Hautepierre) on 04/05/2016 at 09h45 (session 7).

Please check the Conference website for more details:

e-MRS 2016 Website

Tag: Immodgel

Press Release: Antimicrobial Film for Future Implants

List of publications in 2014

List of publications in 2015

Conference Presentation: e-MRS 2016 Lille France

Conference Presentation: e-MRS 2016 Lille France